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Prucalopride inhibits the glioma cells proliferation and induces autophagy via AKT-mTOR pathway

BACKGROUNDS: Glioma is the most fatal primary brain glioma in central nervous system mainly attributed to its high invasion. Prucalopride, a Serotonin-4 (5-HT4) receptor agonist, has been reported to regulate neurodevelopment. This study aimed to investigate the influence of the Prucalopride on glio...

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Publicat a:BMC Neurol
Autors principals: Qiao, Hong, Wang, Yong-Bo, Gao, Yu-Mei, Bi, Li-Li
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985575/
https://ncbi.nlm.nih.gov/pubmed/29866060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12883-018-1083-7
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