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Aging genomes: A necessary evil in the logic of life
Genomes are inherently unstable because of the need for DNA sequence variation as a substrate for evolution through natural selection. However, most multicellular organisms have postmitotic tissues, with limited opportunity for selective removal of cells harboring persistent damage and deleterious m...
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| Published in: | Bioessays |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5985526/ https://ncbi.nlm.nih.gov/pubmed/24464418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300127 |
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