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Exposure of Human CD8(+) T Cells to Type-2 Cytokines Impairs Division and Differentiation and Induces Limited Polarization

Effector CD8(+) T cells generally produce type-1 cytokines and mediators of the perforin/granzyme cytolytic pathway, yet type-2-polarized CD8(+) cells (Tc2) are detected in type-2 (T2) cytokine-driven diseases such as asthma. It is unclear whether T2 cytokine exposure during activation is sufficient...

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Detaylı Bibliyografya
Yayımlandı:Front Immunol
Asıl Yazarlar: Fox, Annette, Harland, Kim L., Kedzierska, Katherine, Kelso, Anne
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985406/
https://ncbi.nlm.nih.gov/pubmed/29892290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01141
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