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Exposure of Human CD8(+) T Cells to Type-2 Cytokines Impairs Division and Differentiation and Induces Limited Polarization
Effector CD8(+) T cells generally produce type-1 cytokines and mediators of the perforin/granzyme cytolytic pathway, yet type-2-polarized CD8(+) cells (Tc2) are detected in type-2 (T2) cytokine-driven diseases such as asthma. It is unclear whether T2 cytokine exposure during activation is sufficient...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5985406/ https://ncbi.nlm.nih.gov/pubmed/29892290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01141 |
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