The Absent in Melanoma 2-Like Receptor IFN-Inducible Protein 16 as an Inflammasome Regulator in Systemic Lupus Erythematosus: The Dark Side of Sensing Microbes

Absent in melanoma 2 (AIM2)-like receptors (ALRs) are a newly characterized class of pathogen recognition receptors (PRRs) involved in cytosolic and nuclear pathogen DNA recognition. In recent years, two ALR family members, the interferon (IFN)-inducible protein 16 (IFI16) and AIM2, have been linked...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Caneparo, Valeria, Landolfo, Santo, Gariglio, Marisa, De Andrea, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985366/
https://ncbi.nlm.nih.gov/pubmed/29892303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01180
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