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Prolyl carboxypeptidase in Agouti-related Peptide neurons modulates food intake and body weight

OBJECTIVE: Prolyl carboxypeptidase (PRCP) plays a role in the regulation of energy metabolism by inactivating hypothalamic α-melanocyte stimulating hormone (α-MSH) levels. Although detected in the arcuate nucleus, limited PRCP expression has been observed in the arcuate POMC neurons, and its site of...

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Publicat a:Mol Metab
Autors principals: Bruschetta, Giuseppe, Jin, Sungho, Kim, Jung Dae, Diano, Sabrina
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985234/
https://ncbi.nlm.nih.gov/pubmed/29459251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.02.003
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