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Prolyl Carboxypeptidase Regulates Energy Expenditure and the Thyroid Axis
Hypothalamic α-melanocyte-stimulating hormone (α-MSH) plays a central role in regulating energy uptake and expenditure. Prolyl carboxypeptidase (PRCP), a protease expressed in the hypothalamus, is responsible for the degradation of α-MSH. PRCP null animals (PRCP(gt/gt) mice) display elevated α-MSH i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3275392/ https://ncbi.nlm.nih.gov/pubmed/22202165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1399 |
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