Modeling human pancreatic beta cell dedifferentiation

OBJECTIVE: Dedifferentiation could explain reduced functional pancreatic β-cell mass in type 2 diabetes (T2D). METHODS: Here we model human β-cell dedifferentiation using growth factor stimulation in the human β-cell line, EndoC-βH1, and human pancreatic islets. RESULTS: Fibroblast growth factor 2 (...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Mol Metab
Hlavní autoři: Diedisheim, Marc, Oshima, Masaya, Albagli, Olivier, Huldt, Charlotte Wennberg, Ahlstedt, Ingela, Clausen, Maryam, Menon, Suraj, Aivazidis, Alexander, Andreasson, Anne-Christine, Haynes, William G., Marchetti, Piero, Marselli, Lorella, Armanet, Mathieu, Chimienti, Fabrice, Scharfmann, Raphael
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985229/
https://ncbi.nlm.nih.gov/pubmed/29472102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.02.002
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky