FRET Image Correlation Spectroscopy Reveals RNAPII-Independent P-TEFb Recruitment on Chromatin

Biochemical studies have revealed that the RNA Polymerase II (RNAPII) pause release is triggered by phosphorylation of the transcription machinery by the positive transcription elongation factor b (P-TEFb). However, there are no direct report that P-TEFb and RNA polymerase II interact in single livi...

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Publicat a:Biophys J
Autors principals: Bidaux, Gabriel, Le Nézet, Corentin, Pisfil, Mariano Gonzalez, Henry, Mélanie, Furlan, Alessandro, Bensaude, Oliver, Vandenbunder, Bernard, Héliot, Laurent
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2018
Matèries:
Nucleic Acids and Genome Biophysics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985016/
https://ncbi.nlm.nih.gov/pubmed/29414698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.11.3783
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