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Dynamics of Chromatin Fibers: Comparison of Monte Carlo Simulations with Force Spectroscopy

To elucidate conformational dynamics of chromatin fibers, we compared available force-spectroscopy measurements with extensive Monte Carlo simulations of nucleosome arrays under external force. Our coarse-grained model of chromatin includes phenomenological energy terms for the DNA-histone adhesion...

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Détails bibliographiques
Publié dans:Biophys J
Auteurs principaux: Norouzi, Davood, Zhurkin, Victor B.
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225046/
https://ncbi.nlm.nih.gov/pubmed/30236784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.06.032
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