Contactin-2, a synaptic and axonal protein, is reduced in cerebrospinal fluid and brain tissue in Alzheimer’s disease

BACKGROUND: Synaptic and axonal loss are two major mechanisms underlying Alzheimer’s disease (AD) pathogenesis, and biomarkers reflecting changes in these cellular processes are needed for early diagnosis and monitoring the progression of AD. Contactin-2 is a synaptic and axonal membrane protein tha...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Chatterjee, Madhurima, Del Campo, Marta, Morrema, Tjado H. J., de Waal, Matthijs, van der Flier, Wiesje M., Hoozemans, Jeroen J. M., Teunissen, Charlotte E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984818/
https://ncbi.nlm.nih.gov/pubmed/29859129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-018-0383-x
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