Contactin-2, a synaptic and axonal protein, is reduced in cerebrospinal fluid and brain tissue in Alzheimer’s disease

BACKGROUND: Synaptic and axonal loss are two major mechanisms underlying Alzheimer’s disease (AD) pathogenesis, and biomarkers reflecting changes in these cellular processes are needed for early diagnosis and monitoring the progression of AD. Contactin-2 is a synaptic and axonal membrane protein tha...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Alzheimers Res Ther
Main Authors: Chatterjee, Madhurima, Del Campo, Marta, Morrema, Tjado H. J., de Waal, Matthijs, van der Flier, Wiesje M., Hoozemans, Jeroen J. M., Teunissen, Charlotte E.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984818/
https://ncbi.nlm.nih.gov/pubmed/29859129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-018-0383-x
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