Neurogranin as a Cerebrospinal Fluid Biomarker for Synaptic Loss in Symptomatic Alzheimer Disease

IMPORTANCE: Neurogranin (NGRN) seems to be a promising novel cerebrospinal fluid (CSF) biomarker for synaptic loss; however, clinical, and especially longitudinal, data are sparse. OBJECTIVE: To examine the utility of NGRN, with repeated CSF sampling, for diagnosis, prognosis, and monitoring of Alzh...

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Vydáno v:JAMA Neurol
Hlavní autoři: Kester, Maartje I., Teunissen, Charlotte E., Crimmins, Daniel L., Herries, Elizabeth M., Ladenson, Jack. H., Scheltens, Philip, van der Flier, Wiesje M., Morris, John C., Holtzman, David M., Fagan, Anne M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694558/
https://ncbi.nlm.nih.gov/pubmed/26366630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2015.1867
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