Neurogranin as a Cerebrospinal Fluid Biomarker for Synaptic Loss in Symptomatic Alzheimer Disease

IMPORTANCE: Neurogranin (NGRN) seems to be a promising novel cerebrospinal fluid (CSF) biomarker for synaptic loss; however, clinical, and especially longitudinal, data are sparse. OBJECTIVE: To examine the utility of NGRN, with repeated CSF sampling, for diagnosis, prognosis, and monitoring of Alzh...

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Publicat a:JAMA Neurol
Autors principals: Kester, Maartje I., Teunissen, Charlotte E., Crimmins, Daniel L., Herries, Elizabeth M., Ladenson, Jack. H., Scheltens, Philip, van der Flier, Wiesje M., Morris, John C., Holtzman, David M., Fagan, Anne M.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694558/
https://ncbi.nlm.nih.gov/pubmed/26366630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2015.1867
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