Lipidomic profiling links the Fanconi anemia pathway to glycosphingolipid metabolism in head and neck cancer cells

PURPOSE: Mutations in Fanconi anemia (FA) genes are common in sporadic squamous cell carcinoma of the head and neck (HNSCC) and we have previously demonstrated that FA pathway depletion in HNSCC cell lines stimulates invasion. The goal of our studies was to use a systems approach in order to define...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Zhao, Xueheng, Brusadelli, Marion G., Sauter, Sharon, Kovacic, Melinda Butsch, Zhang, Wujuan, Romick-Rosendale, Lindsey E., Lambert, Paul F., Setchell, Kenneth D.R., Wells, Susanne I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984686/
https://ncbi.nlm.nih.gov/pubmed/29530934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-3686
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