Lipidomic profiling links the Fanconi anemia pathway to glycosphingolipid metabolism in head and neck cancer cells

PURPOSE: Mutations in Fanconi anemia (FA) genes are common in sporadic squamous cell carcinoma of the head and neck (HNSCC) and we have previously demonstrated that FA pathway depletion in HNSCC cell lines stimulates invasion. The goal of our studies was to use a systems approach in order to define...

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Bibliographic Details
Published in:Clin Cancer Res
Main Authors: Zhao, Xueheng, Brusadelli, Marion G., Sauter, Sharon, Kovacic, Melinda Butsch, Zhang, Wujuan, Romick-Rosendale, Lindsey E., Lambert, Paul F., Setchell, Kenneth D.R., Wells, Susanne I.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984686/
https://ncbi.nlm.nih.gov/pubmed/29530934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-3686
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