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Regional expression of genes mediating trans-synaptic alpha-synuclein transfer predicts regional atrophy in Parkinson disease

Multiple genes have been implicated in Parkinson disease pathogenesis, but the relationship between regional expression of these genes and regional dysfunction across the brain is unknown. We address this question by joint analysis of high resolution magnetic resonance imaging data from the Parkinso...

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Publicat a:Neuroimage Clin
Autors principals: Freeze, Benjamin, Acosta, Diana, Pandya, Sneha, Zhao, Yize, Raj, Ashish
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984599/
https://ncbi.nlm.nih.gov/pubmed/29868450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2018.01.009
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