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Alpha-Synuclein Loss in Spinal Muscular Atrophy

Spinal muscular atrophy, the most prevalent hereditary motor neuron disease, is caused by mutations in the survival motor neuron (SMN) 1 gene. A significant reduction in the encoded SMN protein leads to the degeneration of motor neurons. However, the molecular events leading to this process are not...

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Détails bibliographiques
Auteurs principaux: Acsadi, Gyula, Li, Xingli, Murphy, Kelley J., Swoboda, Kathryn J., Parker, Graham C.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918138/
https://ncbi.nlm.nih.gov/pubmed/20640532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-010-9422-1
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