Treatment of collagenase-induced osteoarthritis with a viral vector encoding TSG-6 results in ectopic bone formation

OBJECTIVE: Tumor necrosis factor-inducible gene 6 (TSG-6) has anti-inflammatory and chondroprotective effects in mouse models of inflammatory arthritis. Because cartilage damage and inflammation are also observed in osteoarthritis (OA), we determined the effect of viral overexpression of TSG-6 in ex...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Broeren, Mathijs G.A., Di Ceglie, Irene, Bennink, Miranda B., van Lent, Peter L.E.M., van den Berg, Wim B., Koenders, Marije I., Blaney Davidson, Esmeralda N., van der Kraan, Peter M., van de Loo, Fons A.J.
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2018
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984587/
https://ncbi.nlm.nih.gov/pubmed/29868252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.4771
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