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Treating hematological malignancies with drugs inhibiting ribosome biogenesis: when and why

It is well known that chemotherapy can cure only some cancers in advanced stage, mostly those with an intact p53 pathway. Hematological cancers such as lymphoma and certain forms of leukemia are paradigmatic examples of such scenario. Recent evidence indicates that the efficacy of many of the alkyla...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Hematol Oncol
Hauptverfasser: Derenzini, Enrico, Rossi, Alessandra, Treré, Davide
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984324/
https://ncbi.nlm.nih.gov/pubmed/29855342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-018-0609-1
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