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Treating hematological malignancies with drugs inhibiting ribosome biogenesis: when and why

It is well known that chemotherapy can cure only some cancers in advanced stage, mostly those with an intact p53 pathway. Hematological cancers such as lymphoma and certain forms of leukemia are paradigmatic examples of such scenario. Recent evidence indicates that the efficacy of many of the alkyla...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Derenzini, Enrico, Rossi, Alessandra, Treré, Davide
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984324/
https://ncbi.nlm.nih.gov/pubmed/29855342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-018-0609-1
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