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The emerging role of RNA polymerase I transcription machinery in human malignancy: a clinical perspective

Ribosome biogenesis – the complex and highly coordinated cellular process leading to the production of ribosomes – is strictly dependent on the activity of RNA polymerase I (Pol I) transcriptional machinery. Pol I activity is continually increased in proliferating cells to sustain the increased dema...

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Библиографические подробности
Главные авторы: Montanaro, Lorenzo, Treré, Davide, Derenzini, Massimo
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722134/
https://ncbi.nlm.nih.gov/pubmed/23888116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S36627
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