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Total Synthesis of the Marine Phosphomacrolide, (−)-Enigmazole A, Exploiting Multicomponent Type I Anion Relay Chemistry (ARC) in Conjunction with a Late Stage Petasis-Ferrier Union/Rearrangement

An effective late-stage large-fragment union/rearrangement exploiting the Petasis-Ferrier protocol, in conjunction with multicomponent Type I Anion Relay Chemistry (ARC) to access advanced intermediates, permits completion of a convergent, stereocontrolled total synthesis of the architecturally comp...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Ai, Yanran, Kozytska, Mariya V., Zou, Yike, Khartulyari, Anton S., Maio, William A., Smith, Amos B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984197/
https://ncbi.nlm.nih.gov/pubmed/29786446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.8b00899
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