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The mre11A470T mutation and homeologous interactions increase error-prone BIR
In the absence of the RNA-templated reverse transcriptase, telomerase, the predominant means of terminal addition, arises from break-induced replication (BIR) at multiple homologous subtelomeric Y′ loci and among internal homeologous (imperfect) (polyG1-3T) tracts. These last tracts are interspersed...
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| Publié dans: | Gene |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5984183/ https://ncbi.nlm.nih.gov/pubmed/29705126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2018.04.057 |
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