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An mre11 Mutation That Promotes Telomere Recombination and an Efficient Bypass of Senescence
Preventing the formation of dysfunctional telomeres is essential for genomic stability. In most organisms, the ribo-nucleoprotein reverse transcriptase telomerase is responsible for telomere GT-strand elongation. However, in telomerase-negative cells, low-frequency recombination mechanisms can avert...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2907200/ https://ncbi.nlm.nih.gov/pubmed/20421597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.117598 |
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