Cargando...
Multiple roles for Mre11 at uncapped telomeres
Progressive telomere attrition or uncapping of the shelterin complex elicits a DNA damage response (DDR) as a result of a cell’s inability to distinguish dysfunctional telomeric ends from DNA double-strand breaks (DSBs)1. Telomere deprotection activates both ataxia telangiectasia mutated (ATM) and t...
Gardado en:
| Main Authors: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760383/ https://ncbi.nlm.nih.gov/pubmed/19633651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08196 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|