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The Mre11 Complex and the Response to Dysfunctional Telomeres

In this study, we examine the telomeric functions of the mammalian Mre11 complex by using hypomorphic Mre11 and Nbs1 mutants (Mre11(ATLD1/ATLD1) and Nbs1(Δ)(B/)(ΔB), respectively). No telomere shortening was observed in Mre11(ATLD1/ATLD1) cells after extensive passage through culture, and the rate o...

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Bibliografiske detaljer
Main Authors: Attwooll, Claire L., Akpınar, Müge, Petrini, John H. J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2756889/
https://ncbi.nlm.nih.gov/pubmed/19667076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00479-09
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