Improvement of Cell Cycle Lifespan and Genetic Damage Susceptibility of Human Mesenchymal Stem Cells by Hypoxic Priming

Hypoxic culture is widely recognized as a method to efficiently expand human mesenchymal stem cells (MSCs) without loss of stem cell properties. However, the molecular basis of how hypoxia priming benefits MSC expansion remains unclear. We report that hypoxic priming markedly extends the cell cycle...

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Veröffentlicht in:Int J Stem Cells
Hauptverfasser: Lee, Chang-Woo, Kang, Dongrim, Kim, Ae-Kyeong, Kim, Dong-Young, Kim, Dong-Ik
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Society for Stem Cell Research 2018
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984059/
https://ncbi.nlm.nih.gov/pubmed/29699381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15283/ijsc17054
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