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Hypoxia Upregulates Mitotic Cyclins Which Contribute to the Multipotency of Human Mesenchymal Stem Cells by Expanding Proliferation Lifespan

Hypoxic culture is widely recognized as a method to efficiently expand human mesenchymal stem cells (MSCs) without loss of stem cell properties. However, the molecular basis of how hypoxia priming benefits MSC expansion remains unclear. In this report, our systemic quantitative proteomic and RT-PCR...

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Detalhes bibliográficos
Publicado no:Mol Cells
Main Authors: Lee, Janet, Kim, Hyun-Soo, Kim, Su-Min, Kim, Dong-Ik, Lee, Chang-Woo
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Molecular and Cellular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881094/
https://ncbi.nlm.nih.gov/pubmed/29463071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2018.2231
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