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Improvement of Cell Cycle Lifespan and Genetic Damage Susceptibility of Human Mesenchymal Stem Cells by Hypoxic Priming

Hypoxic culture is widely recognized as a method to efficiently expand human mesenchymal stem cells (MSCs) without loss of stem cell properties. However, the molecular basis of how hypoxia priming benefits MSC expansion remains unclear. We report that hypoxic priming markedly extends the cell cycle...

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Pubblicato in:Int J Stem Cells
Autori principali: Lee, Chang-Woo, Kang, Dongrim, Kim, Ae-Kyeong, Kim, Dong-Young, Kim, Dong-Ik
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Society for Stem Cell Research 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984059/
https://ncbi.nlm.nih.gov/pubmed/29699381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15283/ijsc17054
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