Combined inhibition of JAK(1,2)/Stat3-PD-L1 signaling pathway suppresses the immune escape of castration-resistant prostate cancer to NK cells in hypoxia

Castration-resistant prostate cancer (CRPC) is difficult to treat in current clinical practice. Hypoxia is an important feature of the CRPC microenvironment and is closely associated with the progress of CRPC invasion. However, no research has been performed on the immune escape of CRPC from NK cell...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Med Rep
Main Authors: Xu, Li-Jun, Ma, Qi, Zhu, Jin, Li, Jian, Xue, Bo-Xin, Gao, Jie, Sun, Chuan-Yang, Zang, Ya-Chen, Zhou, Yi-Bin, Yang, Dong-Rong, Shan, Yu-Xi
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2018
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983983/
https://ncbi.nlm.nih.gov/pubmed/29693186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.8905
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