GDNF secreted by nerves enhances PD-L1 expression via JAK2-STAT1 signaling activation in HNSCC

Programmed death ligand 1 (PD-L1) functions as a key immune inhibitory factor by binding with its receptor, programmed death 1 (PD-1), to induce immune cell dysfunction and escape of the immune system. However, the mechanisms of PD-L1 expression under growth factor stimulation are not well character...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncoimmunology
Prif Awduron: Lin, Chengzhong, Cao, Wei, Ren, Zhenhu, Tang, Yu, Zhang, Chunye, Yang, Rong, Chen, Yiming, Liu, Zheqi, Peng, Canbang, Wang, Lizhen, Wang, Xu, Ji, Tong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2017
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674951/
https://ncbi.nlm.nih.gov/pubmed/29147602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1353860
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