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PIMT/NCOA6IP Deletion in the Mouse Heart Causes Delayed Cardiomyopathy Attributable to Perturbation in Energy Metabolism

PIMT/NCOA6IP, a transcriptional coactivator PRIP/NCOA6 binding protein, enhances nuclear receptor transcriptional activity. Germline disruption of PIMT results in early embryonic lethality due to impairment of development around blastocyst and uterine implantation stages. We now generated mice with...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Jia, Yuzhi, Liu, Ning, Viswakarma, Navin, Sun, Ruya, Schipma, Mathew J., Shang, Meng, Thorp, Edward B., Kanwar, Yashpal S., Thimmapaya, Bayar, Reddy, Janardan K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983783/
https://ncbi.nlm.nih.gov/pubmed/29772707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19051485
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