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PIMT/NCOA6IP Deletion in the Mouse Heart Causes Delayed Cardiomyopathy Attributable to Perturbation in Energy Metabolism

PIMT/NCOA6IP, a transcriptional coactivator PRIP/NCOA6 binding protein, enhances nuclear receptor transcriptional activity. Germline disruption of PIMT results in early embryonic lethality due to impairment of development around blastocyst and uterine implantation stages. We now generated mice with...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Jia, Yuzhi, Liu, Ning, Viswakarma, Navin, Sun, Ruya, Schipma, Mathew J., Shang, Meng, Thorp, Edward B., Kanwar, Yashpal S., Thimmapaya, Bayar, Reddy, Janardan K.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983783/
https://ncbi.nlm.nih.gov/pubmed/29772707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19051485
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