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Targeting Splicing in Prostate Cancer
Over 95% of human genes are alternatively spliced, expressing splice isoforms that often exhibit antagonistic functions. We describe genes whose alternative splicing has been linked to prostate cancer; namely VEGFA, KLF6, BCL2L2, ERG, and AR. We discuss opportunities to develop novel therapies that...
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| Udgivet i: | Int J Mol Sci |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5983716/ https://ncbi.nlm.nih.gov/pubmed/29693622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19051287 |
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