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Aberrant Alternative Splicing Is Another Hallmark of Cancer

The vast majority of human genes are alternatively spliced. Not surprisingly, aberrant alternative splicing is increasingly linked to cancer. Splice isoforms often encode proteins that have distinct and even antagonistic properties. The abnormal expression of splice factors and splice factor kinases...

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Bibliografiske detaljer
Hovedforfatter: Ladomery, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786539/
https://ncbi.nlm.nih.gov/pubmed/24101931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/463786
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