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Aberrant Alternative Splicing Is Another Hallmark of Cancer

The vast majority of human genes are alternatively spliced. Not surprisingly, aberrant alternative splicing is increasingly linked to cancer. Splice isoforms often encode proteins that have distinct and even antagonistic properties. The abnormal expression of splice factors and splice factor kinases...

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Detalhes bibliográficos
Autor principal: Ladomery, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786539/
https://ncbi.nlm.nih.gov/pubmed/24101931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/463786
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