Doxycycline Impairs Mitochondrial Function and Protects Human Glioma Cells from Hypoxia-Induced Cell Death: Implications of Using Tet-Inducible Systems

Inducible gene expression is an important tool in molecular biology research to study protein function. Most frequently, the antibiotic doxycycline is used for regulation of so-called tetracycline (Tet)-inducible systems. In contrast to stable gene overexpression, these systems allow investigation o...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Luger, Anna-Luisa, Sauer, Benedikt, Lorenz, Nadja I., Engel, Anna L., Braun, Yannick, Voss, Martin, Harter, Patrick N., Steinbach, Joachim P., Ronellenfitsch, Michael W.
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983704/
https://ncbi.nlm.nih.gov/pubmed/29772845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19051504
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