Insights into the Origin of Distinct Medin Fibril Morphologies Induced by Incubation Conditions and Seeding

Incubation conditions are an important factor to consider when studying protein aggregation in vitro. Here, we employed biophysical methods and atomic force microscopy to show that agitation dramatically alters the morphology of medin, an amyloid protein deposited in the aorta. Agitation reduces the...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Davies, Hannah A., Lee, Chiu Fan, Miller, Leanne, Liu, Lu-Ning, Madine, Jillian
Format: Artigo
Language:Inglês
Published: MDPI 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983645/
https://ncbi.nlm.nih.gov/pubmed/29751581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19051357
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