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Autophagic Regulation of p62 is Critical for Cancer Therapy
Sequestosome1 (p62/SQSTM 1) is a multidomain protein that interacts with the autophagy machinery as a key adaptor of target cargo. It interacts with phagophores through the LC3-interacting (LIR) domain and with the ubiquitinated protein aggregates through the ubiquitin-associated domain (UBA) domain...
Guardat en:
| Publicat a: | Int J Mol Sci |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5983640/ https://ncbi.nlm.nih.gov/pubmed/29738493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19051405 |
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