TRIM59 promotes breast cancer motility by suppressing p62-selective autophagic degradation of PDCD10

Cancer cells adopt various modes of migration during metastasis. How the ubiquitination machinery contributes to cancer cell motility remains underexplored. Here, we report that tripartite motif (TRIM) 59 is frequently up-regulated in metastatic breast cancer, which is correlated with advanced clini...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Tan, Peng, Ye, Youqiong, He, Lian, Xie, Jiansheng, Jing, Ji, Ma, Guolin, Pan, Hongming, Han, Leng, Han, Weidong, Zhou, Yubin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245796/
https://ncbi.nlm.nih.gov/pubmed/30408026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000051
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