TRIM59 promotes breast cancer motility by suppressing p62-selective autophagic degradation of PDCD10

Cancer cells adopt various modes of migration during metastasis. How the ubiquitination machinery contributes to cancer cell motility remains underexplored. Here, we report that tripartite motif (TRIM) 59 is frequently up-regulated in metastatic breast cancer, which is correlated with advanced clini...

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Библиографические подробности
Опубликовано в: :PLoS Biol
Главные авторы: Tan, Peng, Ye, Youqiong, He, Lian, Xie, Jiansheng, Jing, Ji, Ma, Guolin, Pan, Hongming, Han, Leng, Han, Weidong, Zhou, Yubin
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245796/
https://ncbi.nlm.nih.gov/pubmed/30408026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000051
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