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Why Two? On the Role of (A-)Symmetry in Negative Supercoiling of DNA by Gyrase
Gyrase is a type IIA topoisomerase that catalyzes negative supercoiling of DNA. The enzyme consists of two GyrA and two GyrB subunits. It is believed to introduce negative supercoils into DNA by converting a positive DNA node into a negative node through strand passage: First, it cleaves both DNA st...
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| Pubblicato in: | Int J Mol Sci |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5983639/ https://ncbi.nlm.nih.gov/pubmed/29772727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19051489 |
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