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Effects of COMT genotype and tolcapone on lapses of sustained attention after sleep deprivation in healthy young men
Tolcapone, a brain penetrant selective inhibitor of catechol-O-methyltransferase (COMT) devoid of psychostimulant properties, improves cognition and cortical information processing in rested volunteers, depending on the genotype of the functional Val158Met polymorphism of COMT. The impact of this co...
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| Publié dans: | Neuropsychopharmacology |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer International Publishing
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5983551/ https://ncbi.nlm.nih.gov/pubmed/29472644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0018-8 |
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