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PI3K: A Crucial Piece in the RAS Signaling Puzzle
RAS proteins are key signaling switches essential for control of proliferation, differentiation, and survival of eukaryotic cells. RAS proteins are mutated in 30% of human cancers. In addition, mutations in upstream or downstream signaling components also contribute to oncogenic activation of the pa...
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| Published in: | Cold Spring Harb Perspect Med |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5983164/ https://ncbi.nlm.nih.gov/pubmed/28847905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a031450 |
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