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A Cloning-Free Method for CRISPR/Cas9-Mediated Genome Editing in Fission Yeast

The CRISPR/Cas9 system, which relies on RNA‐guided DNA cleavage to induce site-specific DNA double-strand breaks, is a powerful tool for genome editing. This system has been successfully adapted for the fission yeast Schizosaccharomyces pombe by expressing Cas9 and the single-guide RNA (sgRNA) from...

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Bibliographische Detailangaben
Veröffentlicht in:G3 (Bethesda)
Hauptverfasser: Zhang, Xiao-Ran, He, Jia-Bei, Wang, Yi-Zheng, Du, Li-Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5982833/
https://ncbi.nlm.nih.gov/pubmed/29703785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.118.200164
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