Peritumoral endothelial indoleamine 2, 3-dioxygenase expression is an early independent marker of disease relapse in colorectal cancer and is influenced by DNA mismatch repair profile

Targeting immune checkpoint molecules has become a major new strategy in the treatment of several cancers. Indoleamine 2,3-dioxygenase (IDO)-inhibitors are a potential next-generation immunotherapy, currently investigated in multiple phase I-III trials. IDO is an intracellular immunosuppressive enzy...

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Опубликовано в: :Oncotarget
Главные авторы: Meireson, Annabel, Chevolet, Inès, Hulstaert, Eva, Ferdinande, Liesbeth, Ost, Piet, Geboes, Karen, De Man, Marc, Van de Putte, Dirk, Verset, Laurine, Kruse, Vibeke, Demetter, Pieter, Brochez, Lieve
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2018
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5982767/
https://ncbi.nlm.nih.gov/pubmed/29861865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25393
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