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IDO Expression in Cancer: Different Compartment, Different Functionality?

Indoleamine 2,3-dioxygenase 1 (IDO1) is a cytosolic haem-containing enzyme involved in the degradation of tryptophan to kynurenine. Although initially thought to be solely implicated in the modulation of innate immune responses during infection, subsequent discoveries demonstrated IDO1 as a mechanis...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Meireson, Annabel, Devos, Michael, Brochez, Lieve
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7541907/
https://ncbi.nlm.nih.gov/pubmed/33072086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.531491
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