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Chimeric Antigen Receptor T-Cells (CAR T-Cells) for Cancer Immunotherapy – Moving Target for Industry?

The first CD19 CAR T-cell products, Kymriah and Yescarta, are entering the US market and also being evaluated for marketing authorization in the EU. This breakthrough has expanded the interest and also investments towards novel chimeric antigen receptor (CAR) designs, both for hematological malignan...

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Dettagli Bibliografici
Pubblicato in:Pharm Res
Autori principali: Salmikangas, Paula, Kinsella, Niamh, Chamberlain, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5982434/
https://ncbi.nlm.nih.gov/pubmed/29855723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-018-2436-z
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