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Chimeric antigen receptor T cell (CAR-T) immunotherapy for solid tumors: lessons learned and strategies for moving forward

Recently, the US Food and Drug Administration (FDA) approved the first chimeric antigen receptor T cell (CAR-T) therapy for the treatment CD19-positive B cell acute lymphoblastic leukemia. While CAR-T has achieved remarkable success in the treatment of hematopoietic malignancies, whether it can bene...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Li, Jian, Li, Wenwen, Huang, Kejia, Zhang, Yang, Kupfer, Gary, Zhao, Qi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809840/
https://ncbi.nlm.nih.gov/pubmed/29433552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-018-0568-6
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