Llwytho...
Thermodynamic and NMR Assessment of Ligand Cooperativity and Intersubunit Communication in Symmetric Dimers: Application to Thymidylate Synthase
Thymidylate synthase (TS) is a homodimeric enzyme with evidence for negative regulation of one protomer while the other protomer acts on substrate, so called half-the-sites reactivity. The mechanisms by which multisubunit allosteric proteins communicate between protomers is not well understood, and...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Front Mol Biosci |
|---|---|
| Prif Awduron: | , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Frontiers Media S.A.
2018
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5981203/ https://ncbi.nlm.nih.gov/pubmed/29888227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00047 |
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