PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer

Background: Chemotherapy is currently evaluated in order to enhance the efficacy of immune checkpoint blockade (ICB) therapy in colorectal cancer. However, the mechanisms by which these drugs could synergize with ICB remains unclear. The impact of chemotherapy on the PD-1/PD-L1 pathway and the resul...

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Bibliografische gegevens
Gepubliceerd in:Oncoimmunology
Hoofdauteurs: Dosset, Magalie, Vargas, Thaiz Rivera, Lagrange, Anaïs, Boidot, Romain, Végran, Frédérique, Roussey, Aurélie, Chalmin, Fanny, Dondaine, Lucile, Paul, Catherine, Lauret Marie-Joseph, Elodie, Martin, François, Ryffel, Bernhard, Borg, Christophe, Adotévi, Olivier, Ghiringhelli, François, Apetoh, Lionel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2018
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980491/
https://ncbi.nlm.nih.gov/pubmed/29872568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1433981
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